| BRCA1_(A300-000A) |
Rabbit polyclonal recognizing a region between residue 1800 and the C-terminus (residue 1863) of human Breast Cancer Gene 1. Antibody Target: BRCA1 |
BRCA1 |
Nuclear phosphoprotein that plays a role in maintaining genomic stability, and acts as a tumor suppressor. Associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. Plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. |
Bethyl Laboratories A300-000A |
Snyder |
Human - BRCA1 (A300-000A)(Western blot,IP-MassSpec)
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GeneCard:BRCA1 |
BRCA1 (A300-000A) |