UCSC Human Gene Sorter

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UCSC Human Gene Sorter

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#

Name

VisiGene

BLASTP
E-Value

Genome Position

Description

n/a

n/a

n/a

n/a

chr10 76,867,171

Probable protein tyrosine phosphatase. Has phosphatase activity with synthetic substrates (PubMed:15252030, PubMed:29106959). Has a phosphatase activity-independent regulatory role in MAP3K5/ASK1- mediated apoptosis, preventing MAP3K5/ASK1 inhibition by AKT1. Shows no phosphatase activity on MAPK1/ERK2, MAPK8/JNK, MAPK14/p38 and MAP3K5/ASK1. (from UniProt Q6B8I1)