UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to MAP3K11

IKBKB — MAP3K11

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

IRef Biogrid Interaction: IKBKB — MAP3K11 (direct interaction, enzymatic study) Hehner et al., Mol Cell Biol 2000 *
IRef Hprd Interaction: IKBKB — MAP3K11 (in vivo) Hehner et al., Mol Cell Biol 2000 *
IRef Innatedb Interaction: IKBKB — MAP3K11 (unknown, -) Hehner et al., Mol Cell Biol 2000 *
IRef Ophid Interaction: IKBKB — MAP3K11 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Zhao et al., J Biol Chem 1999 : The essential features of this cascade are that a mitogen activated protein kinase kinase kinase ( MAP3K ) activates an IkappaB kinase (IKK) that site-specifically phosphorylates IkappaB
Cole et al., Biochim Biophys Acta 2009 (MAP Kinase Signaling System) : Mixed lineage kinase 3 negatively regulates IKK activity and enhances etoposide induced cell death