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Wu et al., J Cell Biochem 2010 : In this study, we demonstrate that NF-kappaB induces TAp63 gene expression ... The responsible elements for NF-kappaB mediated TAp63 induction are located within the region from -784 to -296 bp in the TAp63 promoter, which contains two NF-kappaB binding sites ... Inhibition of NF-kappaB by IkappaBalpha super-repressor or with a chemical inhibitor leads to down regulation of TAp63 mRNA expression and activity
Sen et al., J Biol Chem 2011 : Finally, we showed that TAp63a directly induced RelA transcription by binding to and activating of its promoter and, in turn, leading to activation of the NF-?B dependent cell death genes