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IL4 — JUNB

Text-mined interactions from Literome

Hartenstein et al., EMBO J 2002 (Asthma) : Here we demonstrate that loss of JunB in in vitro polarized Th2 cells led to a dysregulated expression of the Th2-specific cytokines IL-4 and IL-5
Garaude et al., J Immunol 2008 : JunB is a transcriptional activator of various cytokine genes, such as IL-2, IL-4 , and IL-10 ; however, the post-translational modifications that regulate JunB activity in T cells are poorly characterized
Son et al., PloS one 2011 : Overexpression of JUNB together with SATB1 synergistically upregulated IL-4 promoter activity, while knockdown JUNB significantly reduced IL-4 expression ... Our results suggest that the prolonged IL-4 expression in NFAT1 deficient Th2 cells is mediated by preferential binding of JUNB/SATB1 to the IL-4 promoter with permissive chromatin architecture
Li et al., EMBO J 1999 : Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation