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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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GIF — IL4

Text-mined interactions from Literome

Jobin et al., Hum Immunol 2000 (Burns) : The decreasing production of INF-gamma in the presence of IL-4 was significantly increased in the presence of sIL-2Ralpha in media
Alves et al., Parasite Immunol 2004 (Leishmaniasis) : INF-gamma and nitric oxide were detected only in supernatants obtained from CBA mouse lymph node cell cultures, whereas IL-4 was detected in supernatant cultures from both strains of mice
Zhu et al., World J Gastroenterol 2004 (Hepatitis C) : While no antigen-specific IL-4 secretion was detected for all vaccinated animals, HCV antigen-specific INF-gamma secretion was detected for the splenocytes of vaccinated animals
Zhao et al., Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2005 (Rhinitis) : Th1/Th2 ratio showed a clear deviation from normal balance ( P < 0.01 ). INF-gamma decreased ( but P > 0.05 ) and IL-4 clearly increased ( P < 0.01 ) in blood serum or mucosa homogenate
Kim-Saijo et al., Proc Natl Acad Sci U S A 2008 (Hypersensitivity) : During the first 24 h of CD3/CD28 stimulation in vitro, GIF secreted from naïve CD4 cells acted on the same cells, maintained nuclear factor of activated T cells ( NFAT)c2 in the nucleus, and repressed IL-4 mRNA levels