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GIF — IL4
Text-mined interactions from Literome
Jobin et al., Hum Immunol 2000
(Burns) :
The decreasing production of
INF-gamma in the
presence of
IL-4 was significantly increased in the presence of sIL-2Ralpha in media
Alves et al., Parasite Immunol 2004
(Leishmaniasis) :
INF-gamma and nitric oxide were
detected only in supernatants obtained from CBA mouse lymph node cell cultures, whereas
IL-4 was detected in supernatant cultures from both strains of mice
Zhu et al., World J Gastroenterol 2004
(Hepatitis C) :
While no antigen-specific
IL-4 secretion was detected for all vaccinated animals, HCV antigen-specific
INF-gamma secretion was
detected for the splenocytes of vaccinated animals
Zhao et al., Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2005
(Rhinitis) :
Th1/Th2 ratio showed a clear deviation from normal balance ( P < 0.01 ).
INF-gamma decreased ( but P > 0.05 ) and
IL-4 clearly
increased ( P < 0.01 ) in blood serum or mucosa homogenate
Kim-Saijo et al., Proc Natl Acad Sci U S A 2008
(Hypersensitivity) :
During the first 24 h of CD3/CD28 stimulation in vitro,
GIF secreted from naïve CD4 cells acted on the same cells, maintained nuclear factor of activated T cells ( NFAT)c2 in the nucleus, and
repressed IL-4 mRNA levels