Gene interactions and pathways from curated databases and text-mining

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APC — PROCR

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Villegas-Mendez et al., Journal of thrombosis and haemostasis : JTH 2007 : The endothelial cell protein C receptor ( EPCR ) presents protein C to the thrombin : thrombomodulin complex on the endothelium of large vessels, and enhances the generation of activated protein C (APC) and activation of protease activated receptor-1
Ping et al., Dig Dis Sci 2010 (Acute Disease...) : The aim of this study was to demonstrate the effects of APC on expressions of thrombomodulin (TM) and endothelial cell protein C receptor ( EPCR ), and its subsequent effect on the severity of SAP
Lee et al., Exp Mol Med 2013 : Endothelial protein C receptor (EPCR) was expressed by MG63 cells and mediated the protective effect of APC on Zol induced viability