Gene interactions and pathways from curated databases and text-mining

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APC — LPO

Text-mined interactions from Literome

Shah et al., Genetics 2001 : We show, however, that Spo12 is not a potent regulator of Clb-Cdc28 activity and can function independently of either the cyclin dependent kinase inhibitor (CDKi), Sic1, or the anaphase promoting complex (APC) regulator, Hct1. Spo12 protein level is regulated by the APC and the protein is degraded in G1 by an Hct1 dependent mechanism
Varela et al., Genetics 2010 : Given that Spo13 overexpression reduces Pds1 and cyclin B degradation, our findings are consistent with a role for Spo13 in regulating APC , which controls both G2/M and anaphase