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APC — LPO
Text-mined interactions from Literome
Shah et al., Genetics 2001
:
We show, however, that Spo12 is not a potent regulator of Clb-Cdc28 activity and can function independently of either the cyclin dependent kinase inhibitor (CDKi), Sic1, or the anaphase promoting complex (APC) regulator, Hct1.
Spo12 protein level is
regulated by the
APC and the protein is degraded in G1 by an Hct1 dependent mechanism
Varela et al., Genetics 2010
:
Given that Spo13 overexpression reduces Pds1 and cyclin B degradation, our findings are consistent with a
role for
Spo13 in regulating
APC , which controls both G2/M and anaphase