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ICAM1 — TLR4

Text-mined interactions from Literome

Boyd et al., Cardiovasc Res 2006 (Myocarditis) : Ligand activation of TLR2, TLR4 and TLR5, but not TLR3, TLR7 or TLR9, resulted in cardiomyocyte expression of the inflammatory cytokine IL-6, the chemokines KC and MIP-2, and the cell surface adhesion molecule ICAM-1 ... Ligand activation of TLR2, TLR4 and TLR5, but not TLR3, TLR7 or TLR9, resulted in cardiomyocyte expression of the inflammatory cytokine IL-6, the chemokines KC and MIP-2, and the cell surface adhesion molecule ICAM-1
Ao et al., Cytokine 2007 (Endotoxemia...) : The interaction between myocardial depressant factors in endotoxemic cardiac dysfunction : role of TNF-alpha in TLR4 mediated ICAM-1 expression ... The purpose of this study was to determine : whether ICAM-1 knockout improves cardiac function during endotoxemia and whether TLR4 and TNF-alpha regulate LPS induced myocardial ICAM-1 expression ... TNF-alpha is involved in the regulation of myocardial ICAM-1 expression by TLR4
Sawa et al., J Histochem Cytochem 2008 : The LPS induced IL-6, IL-8, VCAM-1, and ICAM-1 production in LEC was suppressed by the introduction of TLR4-specific small interfering RNA, and also by anti-TLR4 , nobiletin, and CAPE pretreatment
Xie et al., Cell Microbiol 2008 (Otitis Media with Effusion) : ICAM-1 upregulation on human monocytes by the LOS required surface CD14, TLR4 , NF-kappaB p65 and c-Jun N-terminal kinase (JNK) activity
Sawa et al., Cell Tissue Res 2008 : The expression of LTA induced E-selectin, ICAM-1 , and VCAM-1 in LEC is suppressed by anti-TLR2 but not by anti-TLR4 and is also suppressed by TLR2-specific short interfering RNA ( siRNA ) but not by siRNA for TLR4
Heo et al., Immunol Lett 2008 (Inflammation) : Moreover, NOS inhibitor ( L-NAME ) and anti-TLR 4mAb reduced the LPS induced NO, IL-8 and VEGF production and ICAM-1 expression
Li et al., DNA Cell Biol 2009 : We found that TLR2 priming downregulates TLR4 transcription, and expression of TLR4 activation induced major histocompatibility complex II ( MHC II ), adhesion molecule intercellular adhesion molecule-1 ( ICAM-1 ), phagocytosis marker CD11b/CD18, and Fcgamma receptor ( FcgammaR ) expression
Song et al., J Surg Res 2011 (Aortic Valve Stenosis...) : Microfilaments facilitate TLR4 mediated ICAM-1 expression in human aortic valve interstitial cells ... This study examines ( 1 ) the role of TLR4 in regulating ICAM-1 expression in human AVICs, ( 2 ) the interaction of ICAM-1 with microfilaments, and ( 3 ) the influence of microfilament integrity on ICAM-1 expression ... This study demonstrates that ( 1 ) LPS stimulated ICAM-1 expression in human AVICs is mediated by TLR4 , ( 2 ) ICAM-1 interacts with microfilaments soon after LPS stimulation, and ( 3 ) microfilament disruption reduces ICAM-1 expression
Farina et al., Ann Rheum Dis 2011 (Scleroderma, Systemic) : dsRNA/poly ( I:C ), but not other TLR ligands, highly stimulated ET-1 protein and mRNA ( EDN1 ), as well as intercellular adhesion molecule-1 ( ICAM-1 ) and IFN regulated MX2, by endothelial cells and dermal fibroblasts
Li et al., Cardiovascular diabetology 2010 : Stimulation of TLR2 or TLR4 induced NF-?B activation, and the expression of ICAM-1 , IL-6 and IL-8
Peng et al., Acta Biochim Biophys Sin (Shanghai) 2012 (Inflammation) : TLR4 inhibition reduced LPS induced upregulation of inducible nitric oxide synthase (iNOS) and ICAM-1 as well as PARP1