Gene interactions and pathways from curated databases and text-mining

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IL4 — SERPINE1

Text-mined interactions from Literome

Dong et al., Hypertens Res 2003 (Acute-Phase Reaction...) : Because the liver is one of the major sources of circulating PAI-1, we here examined the effects of two proinflammatory cytokines, interleukin (IL)-1beta , and IL-6, on PAI-1 production in a human hepatoma cell line, HepG2
van Hinsbergh et al., Blood 1994 : Because genistein also inhibited PAI-1 induction by thrombin and IL-4 , it is likely that genistein does not act on a TNF alpha-receptor coupled protein kinase but on the signal transduction pathway enhancing PAI-1 transcription
Wang et al., Am J Physiol 1997 : Although IL-4 had no effects on SMC tPA, UPA, and PAI-1 production, it potentiated bFGF induced tPA, UPA, and PAI-1 antigens
Li et al., Arterioscler Thromb Vasc Biol 1997 (Arteriosclerosis...) : The positive control interleukin-1 increased both 2/2 and 1/1 PAI-1 mRNA levels by approximately 5- to 6-fold