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AMPH — NOS2
Text-mined interactions from Literome
Nowak et al., Toxicology 2008
(Prenatal Exposure Delayed Effects) :
Also, prenatal Pb ( 2+ ) exposure did not enhance
AMPH- and 7-nitroindazole ( neuronal
nitric oxide synthase inhibitor ) ( 7-NI, 20mg/kg i.p. )
Tocharus et al., Neurosci Lett 2008
:
Pretreatment with either S-methylisothiourea ( S-MT ), a selective iNOS inhibitor, or melatonin, a major secretory product of pineal gland, counteracted the over expression of
iNOS induced by
AMPH in a concentration dependent manner ... The
induction of
iNOS by
AMPH in microglial cells could be an important source of NO in CNS inflammatory disorders associated with the death of neurons and oligodendrocytes