Gene interactions and pathways from curated databases and text-mining

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AMPH — DNM3

Pathways - manually collected, often from reviews:

  • KEGG Fc gamma R-mediated phagocytosis: PIK3CA/PIK3CB/PIK3CD/PIK3CG/PIK3R1/PIK3R2/PIK3R3/PIK3R5 → Complex of AMPH-DNM1-DNM1L-DNM2-DNM3 (protein-protein, activation)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Slepnev et al., J Biol Chem 2000 : The interaction of amphiphysin 1 with either clathrin or AP-2 did not prevent its interaction with dynamin , supporting the existence of tertiary complexes between these proteins
Yoshida et al., EMBO J 2004 : In the presence of liposomes, amphiphysin strongly affected dynamin GTPase activity and the recruitment of dynamin to the liposomes, but this activity was highly dependent on liposome size
Karim et al., Cell Signal 2010 : Binding of Unc119 to dynamin decreases the association with its binding partner amphiphysin , a known regulator of dynamin activation