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STAT1 — TLR10
Text-mined interactions from Literome
Rhee et al., J Biol Chem 2003
:
TLR induced phosphorylation of Ser-727
STAT1 could be blocked by the selective p38 mitogen activated protein kinase inhibitor SB203580 ... Lastly,
TLR4 induced
activation of Ser-727
STAT1 phosphorylation could be blocked by rottlerin, a specific inhibitor of protein kinase C-delta
Shoenfelt et al., J Endotoxin Res 2006
:
Unlike other cell types, the p38 mitogen activated protein kinase was necessary, but not sufficient, for
TLR induced phosphorylation of Ser-727
STAT1 in macrophages
Rothlin et al., Cell 2007
(Inflammation) :
TLR induction of
IFNAR-STAT1 signaling upregulates the TAM system, which in turn usurps the IFNAR-STAT1 cassette to induce the cytokine and TLR suppressors SOCS1 and SOCS3
Tel et al., Cancer Immunol Immunother 2012
:
Furthermore, oxaliplatin decreased
TLR induced
STAT1 and STAT3 expression, and NF-?B mediated responses