◀ Back to APOB

APOB — ATP5O

Text-mined interactions from Literome

Rabini et al., J Clin Endocrinol Metab 1999 (Diabetes Mellitus, Type 1) : IDDM LDL significantly increased the platelet aggregating response to ADP, cytosolic Ca2+ concentrations, and plasma membrane Ca2+-ATPase activity and significantly reduced NOS activity and platelet membrane Na+/K+-ATPase activity compared with those of platelets incubated in buffer or cells incubated with control LDL
Zabe et al., Cell Calcium 1999 : We have previously demonstrated that Cu ( 2+ ) -oxidized LDL inhibits platelet plasma membrane Ca ( 2+ ) -ATPase ( PMCA ) in isolated membranes and causes an increase in cytosolic Ca2+ in resting whole platelets
Sakr et al., J Biol Chem 2001 : Degradation of matrix retained, but not soluble, LDL was also blocked by inhibitors of tyrosine kinase, phosphatidylinositol 3-kinase, and myosin ATPase
Usuki et al., Nutrition & metabolism 2007 : The inhibitory effect of HT-modified LDL on Na+/K+-ATPase activity disappeared when TLp was added to the incubation mixture
Kumar et al., Indian J Pharmacol 2012 (Disease Models, Animal...) : Further, mean arterial blood pressure, heart rate, serum leptin, insulin, LDH, LDL-C, total cholesterol, triglycerides, and apolipoprotein-B levels were enhanced significantly, whereas serum HDL-C, apoliporotein-A1 levels, and cardiac Na ( + ) K ( + ) ATPase , antioxidant enzymes levels were significantly decreased
Zhao et al., Cell Calcium 1996 : Since platelet activation is accompanied by an increase in cytosolic calcium, the effects of oxidized LDL on plasma membrane Ca ( 2+ ) -ATPase , plasma membrane fluidity and cytoplasmic calcium were studied in human platelets and purified platelet plasma membranes ... Our results demonstrate that oxidized LDL , but not native LDL, inhibits the activity of Ca ( 2+ ) -ATPase in purified platelet plasma membranes ( P < 0.01 ) ... Addition of the free radical scavenger alpha-tocopherol had no effect on the ability of oxidized LDL to inhibit the Ca ( 2+ ) -ATPase ... Since no change in membrane fluidity was observed in platelet plasma membranes exposed to oxidized or native LDL as estimated by steady state trimethylammonium diphenylhexatriene ( TMA-DPH ) anisotropy, oxidized LDL does not affect the Ca ( 2+ ) -ATPase by grossly changing the membrane environment