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TAC4 — TRPV1
Text-mined interactions from Literome
Trevisani et al., Br J Pharmacol 2005
(Inflammation) :
Our results provide the first pharmacological evidence that H ( 2 ) S provokes
tachykinin mediated neurogenic inflammatory responses in guinea-pig airways, and that this effect is
mediated by stimulation of
TRPV1 receptors on sensory nerves endings
Philyppov et al., Life Sci 2012
(Diabetes Mellitus, Experimental) :
TRPV1 expressing, capsaicin (CAP)-sensitive afferent fibers innervating bladder in addition to sensory function also exhibit `` efferent '' features consisting in
TRPV1 dependent release of
tachykinins ( TAC ) affecting detrusor smooth muscle ( DSM ) contractions ... Modality of action of APHC-polypeptides via the mechanisms involving decreased
TRPV1 dependent release of TAC from bladder afferents and suppression of
TAC degradation due to their activity as endogenous proteases inhibitors is proposed