Gene interactions and pathways from curated databases and text-mining

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TAC4 — TRPV1

Text-mined interactions from Literome

Trevisani et al., Br J Pharmacol 2005 (Inflammation) : Our results provide the first pharmacological evidence that H ( 2 ) S provokes tachykinin mediated neurogenic inflammatory responses in guinea-pig airways, and that this effect is mediated by stimulation of TRPV1 receptors on sensory nerves endings
Philyppov et al., Life Sci 2012 (Diabetes Mellitus, Experimental) : TRPV1 expressing, capsaicin (CAP)-sensitive afferent fibers innervating bladder in addition to sensory function also exhibit `` efferent '' features consisting in TRPV1 dependent release of tachykinins ( TAC ) affecting detrusor smooth muscle ( DSM ) contractions ... Modality of action of APHC-polypeptides via the mechanisms involving decreased TRPV1 dependent release of TAC from bladder afferents and suppression of TAC degradation due to their activity as endogenous proteases inhibitors is proposed