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PIK3R1 — SP1

Text-mined interactions from Literome

Bae et al., Cancer Res 2006 (Adenocarcinoma...) : The inhibition of PI3K/Akt signaling also prevented Sp1 activation
Rojo et al., Free Radic Biol Med 2006 : Then, we observed with the use of a Sp1-Gal4 chimera that PI3K regulates the transactivating capacity of Sp1
Udelhoven et al., J Endocrinol 2010 : Thus, alternative binding of ZBP89 or SP1 to the described region in the IRS2 promoter regulates neuronal IRS2 expression in a PI3K dependent manner
Liao et al., J Biol Chem 2011 (Breast Neoplasms) : PC4 functions are beyond TSA induced phosphatase release, PI3K mediated Sp1 phosphorylation, and HDAC1/2/mSin3A co-repressor release indicating its role as linker coactivator of Sp1 and the transcriptional machinery
Pang et al., International journal of molecular sciences 2013 : Furthermore, resistin enhanced DNA binding activity of Sp1 with VEGF promoter in a PI3K/Akt dependent manner ... PI3K/Akt activated by resistin led to increasing interaction with Sp1 , triggering a progressive phosphorylation of Sp1 on Thr453 and Thr739, resulting in the upregulation of VEGF expression