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CD79A — PLD4
Text-mined interactions from Literome
Hitomi et al., FEBS Lett 1999
:
Herein we provide biochemical and genetic evidence that cross linking of the
B cell receptor (BCR) induces rapid activation of
PLD through a Syk-, Btk- and phospholipase C (PLC)-gamma2 dependent pathway in DT40 cells ... These results demonstrate that Syk, Btk and PLC-gamma2 are essential for
BCR induced
PLD activation
Snyder et al., Traffic 2006
:
Thus, the investigation of the mechanism by which Y112-LMP2A blocks BCR function revealed an essential
role for
PLD in
BCR trafficking for antigen processing