◀ Back to PLA2G4A

IL4 — PLA2G4A

Text-mined interactions from Literome

Hayashi et al., Cytokine 2000 : These results indicate that IL-1beta induced delayed PGE ( 2 ) generation in these human fibroblasts mainly depends on de novo induction of COX-2 and cPLA(2) , irrespective of the constitutive presence of COX-1, and that IFN-gamma and IL-4 inhibit IL-1beta induced delayed PGE ( 2 ) generation by suppressing, predominantly, COX-2 expression
Escoubet-Lozach et al., Eur Cytokine Netw 2001 : Thus, IL-4 acts differently on cPLA2 , 5-LO and FLAP expression and AA metabolism in peritoneal macrophages depending on their resident or sensitization induced differentiated status
Lefebvre et al., FASEB J 2010 : As negative controls, interleukin-8- and formyl-methionyl-leucyl-phenylalanine elicited migration in vitro was not inhibited either by an LTB ( 4 ) receptor antagonist or by the cPLA(2)alpha inhibitor
Chi et al., Arthritis Rheum 2011 (Arthritis, Rheumatoid) : Cytosolic phospholipase A2 induction and prostaglandin E2 release by interleukin-1ß via the myeloid differentiation factor 88-dependent pathway and cooperation of p300, Akt, and NF-?B activity in human rheumatoid arthritis synovial fibroblasts
Onoe et al., J Immunol 1996 (Bone Resorption) : A small increase ( 1.7-fold ) in cPLA2 mRNA levels was detected in the cultures with IL-1 alpha, but the expression was not affected by IL-13 or IL-4