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MSI1 — MUC4
Text-mined interactions from Literome
Hauber et al., J Allergy Clin Immunol 2005
(Chronic Disease...) :
Niflumic acid and
MSI-2216 reduce TNF-alpha induced
mucin expression in human airway mucosa
Hauber et al., J Endotoxin Res 2007
(Inflammation) :
We also investigated the
effect of NFA and
MSI-2216 on LPS induced
mucin up-regulation
Hauber et al., Laryngoscope 2008
(Hypersensitivity...) :
IL-4, IL-9, and IL-13 significantly increased epithelial mucin expression ( P < .05 ). Dexamethasone reduced Th2 type cytokine
induced mucin expression in a dose dependent manner being statistically significant at concentrations > or=4.0 micromol/L ( IL-4 ) and > or=40.0 micromol/L ( IL-9 and IL-13 ) ( P < .05 ). ACC had no significant effect on IL-4 and IL-13 induced mucin expression, whereas IL-9 induced mucin expression was significantly decreased at concentrations > or=3.0 mmol/L ( P < .05 ). NFA and
MSI-2216 decreased Th2 type cytokine induced mucin expression in a dose dependent manner. This effect was statistically significant at concentrations > or=100 micromol/L ( NFA ) and > or=50 micromol/L ( MSI-2216 ) ( P < .05 )