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MRC1 — MSH3

Text-mined interactions from Literome

Das Gupta et al., Nat Genet 2000 (Colorectal Neoplasms, Hereditary Nonpolyposis) : We have identified novel missense mutations in Saccharomyces cerevisiae MSH6 that appear to inactivate both Msh2p-Msh6p- and Msh2p-Msh3p dependent MMR
Franchitto et al., Oncogene 2003 : In yeast, MSH2 plays an important role in mismatch repair (MMR) and recombination, whereas the function of the mammalian MSH2 protein in recombinational repair is not completely established
Jiang et al., Mol Cell 2005 : Mismatch repair (MMR) is initiated by MutS family proteins ( MSH ) that recognize DNA mismatches and recruit downstream repair factors
Sonntag Brown et al., G3 (Bethesda, Md.) 2013 : Mlh1-Mlh3 also plays a role in DNA mismatch repair (MMR) by interacting with Msh2-Msh3 to repair insertion and deletion mutations
Kumar et al., J Mol Biol 2013 : We identified a set of aromatic residues within the FLY motif of the predicted Msh3 nucleotide binding pocket that are essential for Msh2-Msh3 mediated MMR but are largely dispensable for 3 ' NHTR