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HTT — IKBKAP

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind Interaction: HTT — IKBKAP Goehler et al., Mol Cell 2004
• IRef Bind_translation Interaction: HTT — IKBKAP (affinity chromatography technology) Goehler et al., Mol Cell 2004
• IRef Bind_translation Interaction: HTT — IKBKAP (two hybrid) Goehler et al., Mol Cell 2004
• IRef Biogrid Interaction: HTT — IKBKAP (direct interaction, pull down) Goehler et al., Mol Cell 2004
• IRef Biogrid Interaction: HTT — IKBKAP (direct interaction, two hybrid) Goehler et al., Mol Cell 2004
• IRef Hprd Interaction: HTT — IKBKAP (in vitro) Goehler et al., Mol Cell 2004
• IRef Hprd Interaction: HTT — IKBKAP (two hybrid) Goehler et al., Mol Cell 2004
• IRef Innatedb Interaction: HTT — IKBKAP (unknown, -) Goehler et al., Mol Cell 2004
• IRef Intact Interaction: HTT — IKBKAP (physical association, two hybrid) Goehler et al., Mol Cell 2004
• IRef Intact Interaction: HTT — IKBKAP (physical association, pull down) Goehler et al., Mol Cell 2004

Text-mined interactions from Literome

Khoshnan et al., J Neurosci 2004 (Nerve Degeneration) : In inducible PC12 cells and in HD transgenic mice, mutant Htt activates the IkappaB kinase complex (IKK) , a key regulator of NF-kappaB
Rong et al., J Neurosci 2006 (Huntington Disease...) : Mutant huntingtin also reduces the association of HAP1 with dynactin p150 and kinesin light chain and thereby decreases the intracellular level of TrkA