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CRIPT — DLG4
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Biogrid Interaction:
CRIPT
—
DLG4
(direct interaction, pull down)
Niethammer et al., Neuron 1998*
-
IRef Hprd Interaction:
DLG4
—
CRIPT
(in vitro)
Piserchio et al., J Biol Chem 2002*, Niethammer et al., Neuron 1998*
-
IRef Hprd Interaction:
DLG4
—
CRIPT
(two hybrid)
Piserchio et al., J Biol Chem 2002*, Niethammer et al., Neuron 1998*
-
IRef Intact Interaction:
CRIPT
—
DLG4
(direct interaction, enzyme linked immunosorbent assay)
Lim et al., J Biol Chem 2002
-
IRef Intact Interaction:
CRIPT
—
DLG4
(direct interaction, fluorescence polarization spectroscopy)
Lim et al., J Biol Chem 2002
-
IRef Ophid Interaction:
CRIPT
—
DLG4
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
Text-mined interactions from Literome
Passafaro et al., Nat Neurosci 1999
:
Disrupting the
CRIPT-PSD-95 interaction in cultured hippocampal neurons with a PDZ3-specific peptide
prevented the association of
PSD-95 with microtubules and inhibited the synaptic clustering of PSD-95, chapsyn-110/PSD-93 and GKAP ( a PSD-95 binding protein )
Niethammer et al., Neuron 1998
:
These findings suggest that
CRIPT may
regulate PSD-95 interaction with a tubulin based cytoskeleton in excitatory synapses