Gene interactions and pathways from curated databases and text-mining

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APCS — CD86

Text-mined interactions from Literome

Shi et al., Allergy 2004 : Our data showed that airway eosinophils functioned as CD80- and CD86 dependent antigen presenting cells (APCs) to stimulate sensitized CD4+ lymphocytes to produce interleukin (IL)-4, IL-5, and IL-13, but not interferon (IFN)-gamma in in vitro assay
Hancock et al., Proc Natl Acad Sci U S A 1996 : Alternatively, the ability of CD40 stimulation to induce CD80 ( B7-1 ) and CD86 ( B7-2 ) expression on antigen presenting cells (APCs) has led to the hypothesis that the role of CD40-CD40L interactions in transplant rejection might be indirect, i.e., to promote the costimulatory capacity of APCs