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RLN3 — TIMP2
Text-mined interactions from Literome
Lenhart et al., Endocrinology 2002
:
In the uterine cervix,
relaxin enhanced expression of TIMP-1 and
TIMP-2 ( P < 0.05 ), whereas expression of both TIMP proteins was similar in the vaginal cervix of control and relaxin treated animals
Hossain et al., Biochemistry 2011
(Fibrosis) :
Furthermore, H3
relaxin ( 100 ng/mL ) significantly
inhibited TGF-ß1 stimulated cardiac myofibroblast differentiation and TIMP-1 and
TIMP-2 expression to an equivalent extent as H2 relaxin ( 100 ng/mL ), while also inhibiting Smad2 phosphorylation to approximately half the extent of H2 relaxin ( all p < 0.05 vs TGF-ß1 )