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Ozgen et al., J Biol Chem 2008
:
Adenoviral mediated overexpression of PKCdelta ( but not PKCepsilon or PKCalpha ) activates PKD ; PKCdelta and PKD1-S744E/S748E overexpression both promote CREB-Ser ( 133 ) phosphorylation
Guo et al., J Biol Chem 2011
(Heart Failure) :
Gene silencing studies provide unanticipated evidence that PKD1 down-regulation leads to a compensatory increase in PKD2 activity and that down-regulation of PKD1 ( alone or in combination with PKD2 ) leads to an increase in CREB-Ser ( 133 ) phosphorylation