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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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CREB5 — MAPKAPK2

Text-mined interactions from Literome

Miguel et al., J Biol Chem 2005 (MAP Kinase Signaling System) : These data define a novel mitogenic signaling pathway in osteoblasts whereby ERK1/2 stimulation of CREB phosphorylation and transcriptional activity as well as DNA synthesis are critically dependent on de novo Mapkapk2 synthesis
Tan et al., EMBO J 1996 : We show that MAPKAP kinase-2 phosphorylates CREB at Ser133 in vitro, that the FGF- or stress induced activation of MAPKAP kinase-2 and phosphorylation of CREB and ATF-1 are prevented by similar concentrations of the specific p38 MAP kinase inhibitor SB 203580, and that MAPKAP kinase-2 is the only detectable SB 203580-sensitive CREB kinase in SK-N-MC cell extracts