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SMC3 — TNF

Text-mined interactions from Literome

Cai et al., J Steroid Biochem Mol Biol 2001 : Stimulation of SMC with IL-1beta or TNFalpha led to a time- and dose dependent increase of mRNA levels for 11beta-HSD1, while 11beta-HSD2 mRNA levels decreased
Rödel et al., FEMS Immunol Med Microbiol 2001 (Chlamydia Infections) : In addition, C. pneumoniae infection enhanced the mRNA level of indoleamine 2,3-dioxygenase, an IFN-inducible factor mediating the restriction of intracellular chlamydial growth, in TNF-alpha stimulated SMC
Ivanov et al., J Cardiovasc Pharmacol 2007 (Atherosclerosis) : Stimulation of SMC with tumor necrosis factor-alpha significantly increased production and secretion of such mediators of inflammation as IL-6 and MCP-1 ; addition of 100 microg/mL NM inhibited secretion of MCP-1 and IL-6 by 65 % and 47 %, respectively
Bai et al., Mol Cancer Ther 2009 (Neoplasms) : We found that effective blockage of NF-kappaB had no detectable effect on SM compound 3 (SMC3) induced TNF secretion, suggesting that the induction of TNF by SMC3 is independent of NF-kappaB
Molossi et al., J Cell Physiol 1995 : Thus, our studies suggest that vascular SMC fibronectin synthesis is regulated by reciprocal induction of IL-1 beta and TNF-alpha activity and provide the first demonstration of a ` cytokine loop ' modulating matrix production