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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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IL6 — WNT4

Text-mined interactions from Literome

Gustafson et al., J Biol Chem 2006 (Diabetes Mellitus...) : Remarkably, both IL-6 and TNFalpha maintained and augmented the canonical Wnt signaling associated with low axin and high low density lipoprotein receptor related protein ( LRD ), Dishevelled, and beta-catenin levels
Li et al., Cancer prevention research (Philadelphia, Pa.) 2011 (Neoplasm Invasiveness...) : In this study, we investigated the signal transduction in the AR/TMPRSS2-ERG/Wnt signaling network for studying the aggressive behavior of prostate cancer cells and further assessed the effects of BR-DIM and CDF [ natural agents derived synthetic formulation and analogue of 3,3'-diindolylmethane ( DIM ) and curcumin, respectively, with improved bioavailability ] on the regulation of AR/TMPRSS2-ERG/Wnt signaling
Heijink et al., Thorax 2013 (Pulmonary Disease, Chronic Obstructive) : Exogenously added WNT-4 significantly increased CXCL8/IL-8, IL-6 , CCL5/RANTES, CCL2/MCP-1 and vascular endothelial growth factor ( VEGF ) secretion in 16HBE, but did not affect the canonical WNT target genes MMP-2, MMP-9, fibronectin, ß-catenin, Dickkopf and axin-2, and induced activation of the non-canonical signalling molecule p38