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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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HIF1A — IL6

Text-mined interactions from Literome

Pfäfflin et al., Cell Physiol Biochem 2006 : The IL-6 expression was not affected by reducing HIF-1alpha
Lang et al., Clin Cancer Res 2007 (Neovascularization, Pathologic...) : Hypoxia- and IL-6 mediated activation of HIF-1alpha or STAT3/STAT5 were substantially inhibited by 17-AAG
Nickel et al., Shock 2009 (Disease Models, Animal...) : Because hypoxia-inducible factor (HIF) 1 alpha is expressed during hypoxia and cellular stress and up-regulates the expression of IL-6, we hypothesized that HIF-1 alpha induces the increased cardiac IL-6 after trauma-hemorrhage and that estrogen suppresses this induction
Westra et al., Ann N Y Acad Sci 2009 (Arthritis, Rheumatoid) : Protein and mRNA expression of HIF-1alpha and the effects of inhibitors of the CaMKII-, PI3K-, and ERK pathway on VEGF and IL-6 production were analyzed
Gao et al., Toxicol Appl Pharmacol 2010 : IL-6 induced by Ni/MALP-2 co-exposure was partially dependent on activity of HIF-1alpha and COX-2 as shown by targeted knockdown using siRNA