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HIF1A — IL6
Text-mined interactions from Literome
Pfäfflin et al., Cell Physiol Biochem 2006
:
The
IL-6 expression was not
affected by reducing
HIF-1alpha
Lang et al., Clin Cancer Res 2007
(Neovascularization, Pathologic...) :
Hypoxia- and
IL-6 mediated
activation of
HIF-1alpha or STAT3/STAT5 were substantially inhibited by 17-AAG
Nickel et al., Shock 2009
(Disease Models, Animal...) :
Because hypoxia-inducible factor (HIF) 1 alpha is expressed during hypoxia and cellular stress and up-regulates the expression of IL-6, we hypothesized that
HIF-1 alpha induces the increased cardiac
IL-6 after trauma-hemorrhage and that estrogen suppresses this induction
Westra et al., Ann N Y Acad Sci 2009
(Arthritis, Rheumatoid) :
Protein and mRNA expression of
HIF-1alpha and the
effects of inhibitors of the CaMKII-, PI3K-, and ERK pathway on VEGF and
IL-6 production were analyzed
Gao et al., Toxicol Appl Pharmacol 2010
:
IL-6 induced by Ni/MALP-2 co-exposure was partially
dependent on activity of
HIF-1alpha and COX-2 as shown by targeted knockdown using siRNA