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ECM1 — FGF20
Text-mined interactions from Literome
Nur-E-Kamal et al., Mol Cell Biochem 2008
:
Activation of
fibroblast growth factor receptors ( FGFRs )
requires the formation of a ternary complex between fibroblast growth factors ( FGFs ), FGFRs, and heparan sulfate proteoglycans, which are all located on the cell surface and the basement membrane ( BM )
/extracellular matrix ( ECM )
Uchii et al., Arthritis Res Ther 2008
(Disease Models, Animal...) :
In cultured chondrocytes,
FGF8 induced the release of matrix metalloproteinase 3 and prostaglandin E2, and
caused degradation of the
ECM
Etheredge et al., Invest Ophthalmol Vis Sci 2009
:
The
effects of IGF-I, TGF-beta1,
FGF-2 , and PDGF on proliferation and
ECM production by primary cultured bovine keratocytes were evaluated
Hitraya et al., Lab Invest 1995
:
Heparin alone decreased the mRNA levels for these genes by 60, 77, and 65 %, respectively ; however,
FGF potentiated the negative effect of heparin on
ECM gene expression