We have a suspicion that you are an automated web bot software, not a real user.
To keep our site fast for other users, we have slowed down this page.
The slowdown will gradually disappear.
If you think this is a mistake, please contact us at genome-www@soe.ucsc.edu.
Also note that all data for hgGeneGraph can be obtained through our public MySQL server and
all our software source code is available and can be installed locally onto your own computer.
If you are unsure how to use these resources, do not hesitate to contact us.
UCSC Genome Browser Gene Interaction Graph
JavaScript is disabled in your web browser
You must have JavaScript enabled in your web browser to use the Genome Browser
Gene interactions and pathways from curated databases and text-mining
◀ Back to DDX17
DDX17 — NCOA2
Pathways - manually collected, often from reviews:
NCI Pathway Database Validated nuclear estrogen receptor alpha network :
E2/ERA (dimer)/TIF2/P72 complex (ESR1-NCOA2-DDX17)
→
E2/ERA (dimer)/TIF2 complex (ESR1-NCOA2)
(modification, collaborate)
Watanabe et al., EMBO J 2001
physical interaction
NCI Pathway Database Validated nuclear estrogen receptor alpha network :
E2/ERA (dimer)/TIF2/P72 complex (ESR1-NCOA2-DDX17)
→
P72 (DDX17)
(modification, collaborate)
Watanabe et al., EMBO J 2001
physical interaction
NCI Pathway Database Validated nuclear estrogen receptor alpha network :
E2/ERA (dimer)/TIF2 complex (ESR1-NCOA2)
→
P72 (DDX17)
(modification, collaborate)
Watanabe et al., EMBO J 2001
physical interaction
NCI Pathway Database Validated nuclear estrogen receptor alpha network :
E2/ERA (dimer)/TIF2/P72 complex (ESR1-NCOA2-DDX17)
→
TFF1 (TFF1)
(transcription, activates)
Watanabe et al., EMBO J 2001 , Shao et al., Mol Cell Biol 2002 *
mutant phenotype, physical interaction
NCI Pathway Database Validated nuclear estrogen receptor alpha network :
E2/ERA (dimer)/TIF2/P72 complex (ESR1-NCOA2-DDX17)
→
E2/ERA (dimer)/TIF2/P72/SRA1 complex (ESR1-NCOA2-DDX17-SRA1)
(modification, collaborate)
Watanabe et al., EMBO J 2001
mutant phenotype, physical interaction
NCI Pathway Database Validated nuclear estrogen receptor alpha network :
E2/ERA (dimer)/TIF2/P72 complex (ESR1-NCOA2-DDX17)
→
SRA1 (SRA1)
(modification, collaborate)
Watanabe et al., EMBO J 2001
mutant phenotype, physical interaction
NCI Pathway Database Validated nuclear estrogen receptor alpha network :
E2/ERA (dimer)/TIF2/P72/SRA1 complex (ESR1-NCOA2-DDX17-SRA1)
→
SRA1 (SRA1)
(modification, collaborate)
Watanabe et al., EMBO J 2001
mutant phenotype, physical interaction
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
IRef Biogrid Interaction :
NCOA2
—
DDX17
(physical association, affinity chromatography technology)
Watanabe et al., EMBO J 2001
IRef Biogrid Interaction :
NCOA2
—
DDX17
(direct interaction, two hybrid)
Watanabe et al., EMBO J 2001
IRef Biogrid Interaction :
NCOA2
—
DDX17
(direct interaction, pull down)
Watanabe et al., EMBO J 2001
IRef Hprd Interaction :
NCOA2
—
DDX17
(in vitro)
Watanabe et al., EMBO J 2001
IRef Hprd Interaction :
NCOA2
—
DDX17
(two hybrid)
Watanabe et al., EMBO J 2001
IRef Intact Interaction :
DDX17
—
NCOA2
(physical association, pull down)
Watanabe et al., EMBO J 2001
IRef Intact Interaction :
DDX17
—
NCOA2
(direct interaction, pull down)
Watanabe et al., EMBO J 2001
IRef Intact Interaction :
Complex of ESR1-NCOA2-DDX17-ESR1-DDX17-NCOA2-ESR1-NCOA2-DDX17
(association, anti tag coimmunoprecipitation)
Watanabe et al., EMBO J 2001