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BCL3 — MMP2

Text-mined interactions from Literome

Bae et al., Cancer Res 2006 (Adenocarcinoma...) : Consistently, Bcl-w , but not Bcl-2, overexpression increased matrix metalloproteinase-2 (MMP-2) expression, and synthetic or natural inhibitors of MMP-2 abolished Bcl-w induced cell invasion ... Bcl-w overexpression also activated phosphoinositide 3-kinase (PI3K), Akt, and Sp1, and the blocking effects of each of these components using pharmacologic inhibitors, dominant negative mutants, or small interfering RNA abolished the ability of Bcl-w to induce MMP-2 and cell invasion
Lecoeur et al., Cell death & disease 2012 : Pharmacologic inhibitors of the permeability transition pore, Bax/Bak inhibitors, and recombinant Bcl-2 and Bcl-XL proteins do not reduce Tat induced MMP
Arbab et al., Evidence-based complementary and alternative medicine : eCAM 2012 : We found that dentatin mediated accumulation of reactive oxygen species ( ROS ) and downregulated expression levels of antiapoptotic molecules ( Bcl-2, Bcl-xL , and Survivin ), leading to disruption of mitochondrial membrane potential ( MMP ) , cell membrane permeability, and release of cytochrome c from the mitochondria into the cytosol