Gene interactions and pathways from curated databases and text-mining

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PITX2 — TBX5

Text-mined interactions from Literome

Hilton et al., J Biol Chem 2010 : Pitx2 activated Tbx4, Tbx15, and Mga and repressed Tbx1, Tbx2, Tbx5 , and Tbx6 expression
Lozano-Velasco et al., Cells Tissues Organs 2011 : Additionally, Pitx2c induces the expression of chamber-specific cardiac genes such as Tbx5 , Nppa and Cx40