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BCRP8 — PGP
Text-mined interactions from Literome
Dahan et al., Am J Physiol Gastrointest Liver Physiol 2009
:
In conclusion, efflux transport
mediated by MRP2 and
BCRP , but not
P-gp , shifts sulfasalazine permeability from high to low, thereby enabling its colonic targeting and therapeutic action
Duan et al., PloS one 2009
(Ovarian Neoplasms) :
Coincubating cells with a sublethal concentration of paclitaxel in combination with each of 2,000 small molecule compounds from the National Cancer Institute Diversity Set Library, we identified a previously uncharacterized molecule, NSC23925, that inhibits
Pgp1 and reverses MDR1 ( Pgp1 ) but does not
inhibit MRP or
BCRP mediated MDR