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CEP85 — PTGS2
Text-mined interactions from Literome
Mizumura et al., Clin Exp Allergy 2003
(Influenza, Human...) :
The results showed that ( 1 ) IV infection increases COX-2 expression, cPLA2 phosphorylation and PGE2 release, ( 2 ) ERK, p38 MAPK and JNK were phosphorylated, ( 3 )
CEP-11004 and PD 98059 predominantly
attenuated COX-2 expression and cPLA2 phosphorylation, respectively, ( 4 ) SB 203580 did not remarkably affect COX-2 expression and cPLA2 phosphorylation, and ( 5 ) each inhibitor dose-dependently attenuated PGE2 release by various extents
Fang et al., Int J Gynecol Cancer 2013
:
The inhibitory
effects of
CEP on STAT3 signaling pathway and
COX-2 help us to better understand the radiosensitization of CEP