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PCNA — TNF

Text-mined interactions from Literome

Merli et al., Int J Oncol 1999 (Bone Neoplasms...) : TNF-alpha reduced the expression of the cyclin E-cdk2 complex
Belizário et al., Braz J Med Biol Res 1999 : We examined the effects of TNF ( 1-100 ng/ml ) and butyrolactone I ( 100 microM ), a specific inhibitor of cyclin dependent kinases (CDK) with high selectivity for CDK-1 and CDK-2, on three different cancer cell lines : WEHI, L929 and HeLa S3
Gaiotti et al., Mol Carcinog 2000 : TNF-alpha promoted cell cycle progression by increasing expression of HPV-16 E6/E7 RNAs and enhancing activity of cyclin dependent kinase (cdk)2 and cdc2 after 3 d. Increased kinase activity was mediated by upregulation of cyclins A and B and decreases in cdk inhibitors p21 ( waf ) and p27 ( kip )
Kishore et al., Circ Res 2002 : TNF-alpha inhibited de novo cyclin A mRNA synthesis and suppressed cyclin A promoter activity
Shen et al., J Biol Chem 2004 (Adenocarcinoma...) : Deletion of an E2F recognition site from this reporter eliminates the regulatory effects of both IGF-I and TNFalpha on cyclin A transcription, indicating the essential role of E2F-1 in mediating their cross-talk
Luedemann et al., Alcohol Clin Exp Res 2005 (Alcoholism...) : Inhibition of JNK by over-expression of dominant negative JNK1 substantially reversed ethanol/TNF mediated inhibition of cyclin A expression and EC proliferation, suggesting modulation of JNK1 signaling as the mechanism for ethanol/TNF induced EC dysfunctions
Aggarwal et al., Mol Pharmacol 2006 (Neoplasm Metastasis) : Such TNF induced NF-kappaB regulated gene products involved in cellular proliferation [ cyclooxygenase-2 (COX-2), cyclin D1, and c-myc ], antiapoptosis [ inhibitor of apoptosis protein (IAP)1, IAP2, X-chromosome linked IAP, Bcl-2, Bcl-x ( L ), Bfl-1/A1, TNF receptor associated factor 1, and cellular Fas associated death domain protein-like interleukin-1beta converting enzyme inhibitory protein-like inhibitory protein ], and metastasis ( vascular endothelial growth factor, matrix metalloproteinase-9, and intercellular adhesion molecule-1 ) were also down-regulated by curcumin
Barten et al., Transplant Proc 2005 (Gingival Diseases...) : Compared to CsA therapy, increased TRL concentrations did not further inhibit PCNA expression, inhibited CD25 expression less on days 1 and 2 and equally high on day 3, but inhibited expression of IL-2 and TNF-alpha significantly higher on days 2 and 3 ( P < .05 )
Radeff-Huang et al., J Biol Chem 2007 (Brain Neoplasms...) : Furthermore, cyclin D expression was increased by TNF-alpha in a SphK- and Akt dependent manner ... We conclude that SphK dependent Akt activation plays a significant role in TNF-alpha induced cyclin D expression and cell proliferation
Cho et al., Int J Mol Med 2007 : We found that curcumin inhibited the expression of TNF-alpha induced IL-1beta, IL-6, and TNF-alpha, but not IL-8, in TNF-alpha treated HaCaT cells as well as the TNF-alpha induced cyclin E expression
Ahn et al., Cancer Res 2007 (Skin Neoplasms) : The induction of various antiapoptotic gene products ( MMP-9, cyclin D1, COX-2, IAP1, IAP2, Bcl-2, cFLIP, and XIAP ) by TNF was also abolished in NQO2-/- cells
Long et al., Transplant Proc 2008 : The intragraft expression of TNF-alpha and caspase-3 was strikingly promoted in the normal saline treated group and PCNA attenuated compared to the ALR group
Xing et al., Pharm Biol 2013 : In addition, the effects of total flavonoids on inflammatory molecule expression of cells were tested by immunohistochemistry staining, showing that TNF-a induced expression of PCNA , NF-?B p65, ICAM-1, and VCAM-1 in VSMCs was dose-dependently suppressed by total flavonoids
Ma et al., Archives of medical science : AMS 2013 : Meanwhile, EsA reduced the serum IL-6 and TNF-a levels ( p < 0.05 ), inhibited the expression of PCNA and promoted the expression of caspase-3, Fas and FasL in animals of the treated group ( p < 0.05 )
Sakayama et al., Biochem J 1996 (Bone Neoplasms...) : TNF-alpha also suppressed expression of proliferating cell nuclear antigen , indicating that it had an anti-proliferative activity on OST cells