Gene interactions and pathways from curated databases and text-mining

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ALOX5 — TGFB3

Text-mined interactions from Literome

Uhl et al., J Biol Chem 2002 : 1,25-dihydroxyvitamin D ( 3 ) and transforming growth factor-beta ( TGFbeta ), potent inducers of the 5-LO pathway in myeloid cell lines, increased 5-LO RNA expression in HL-60TB and U937 cells, but co-treatment with AdC was required to achieve 5-LO expression levels in HL-60TB cells that were comparable with wild-type HL-60 cells
Sorg et al., Biochim Biophys Acta 2006 : 1,25-Dihydroxyvitamin D ( 3 ) ( 1,25 ( OH ) ( 2 ) D ( 3 ) ) and transforming growth factor beta ( TGFbeta ) potently induce 5-lipoxygenase (5-LO) in myeloid cells
Seuter et al., Biochem Biophys Res Commun 2006 : 5-Lipoxygenase (5-LO) expression is strongly induced by transforming growth factor-beta ( TGFbeta ) and 1alpha,25-dihydroxyvitamin D ( 3 ) in Mono Mac 6 cells
Brungs et al., Proc Natl Acad Sci U S A 1995 : Sequential induction of 5-lipoxygenase gene expression and activity in Mono Mac 6 cells by transforming growth factor beta and 1,25-dihydroxyvitamin D3