◀ Back to MRE11A
MRE11A — VAV2
Text-mined interactions from Literome
Arthur et al., J Cell Biol 2004
:
Overexpressed
VAV2 and Tiam1 specifically
require Rap1 to promote spreading, even though Rac1 is activated independently of Rap1 ...
Rap1 is
necessary for the accumulation of
VAV2 in membrane protrusions at the cell periphery
Fukuyama et al., Oncogene 2006
:
The c-Src catalysed tyrosine phosphorylation was not sufficient for the activation of
Vav2 and the c-Src induced activation of
Rap1 was additionally
necessary for it, although activated Rap1 alone was not sufficient for the activation of non-tyrosine phosphorylated Vav2 ... This
effect of
Rap1 on
Vav2 was mediated by phosphatidylinositol 3-kinase