Shin et al., J Biol Chem 2001
(Fibrosarcoma) :
Both the Ca ( 2+ ) /calmodulin dependent protein kinase II inhibitor KN62 and the calcineurin inhibitor cyclosporin A enhanced TFP dependent increase of Egr-1 , suggesting that the Ca ( 2+ ) /calmodulindependent pathway plays a role in regulation of Egr-1 expression in HT1080 cells
Mellott et al., FASEB J 2007
(Choline Deficiency) :
Prenatally choline supplemented rats had the highest expression of calcium/calmodulin (CaM) dependent protein kinase ( CaMK) I and insulin-like growth factor (IGF) II ( Igf2 ) in the cortex and of the transcription factor Zif268/EGR1 in the cortex and hippocampus