Gomes et al., Invest Ophthalmol Vis Sci 2005
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Neither FFA nor Gap26 affected the FRAP , indicating that reduction in AA of the PMS induced wave by these agents is not due to a block of gap junction channels
Budanov et al., Cell 2008
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We now demonstrate that the products of two p53 target genes, Sestrin1 and Sestrin2, activate the AMP-responsive protein kinase (AMPK) and target it to phosphorylate TSC2 and stimulate its GAP activity, thereby inhibiting mTOR