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SMAD3 — STK24
Text-mined interactions from Literome
Raftery et al., Dev Biol 1999
:
Work in mammalian tissue culture has elucidated a biochemical model for signal transduction, in which activation of receptor
serine-threonine kinase activity
leads to phosphorylation of specific
Smad proteins and translocation of heteromeric Smad protein complexes to the nucleus
Sauer et al., J Biol Chem 2004
:
Both sphingosine 1-phosphate receptors and the transforming growth factor beta-type I receptor
serine/threonine kinase are
essential for activation of
Smad3 by this lysophospholipid and the dependent biological responses, indicating a novel cross-talk between serine/threonine kinase receptors and G-protein coupled receptors