Gene interactions and pathways from curated databases and text-mining

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PPARA — SLC2A4

Text-mined interactions from Literome

Finck et al., Cell Metab 2005 (Diabetes Mellitus...) : Pharmacologic inhibition of fatty acid oxidation or mitochondrial respiratory coupling prevented the effects of PPARalpha on GLUT4 expression and glucose homeostasis
Gandhi et al., Biochim Biophys Acta 2013 (Diabetes Mellitus, Experimental...) : Insulin sensitization via partial agonism of PPAR? and glucose uptake through translocation and activation of GLUT4 in PI3K/p-Akt signaling pathway by embelin in type 2 diabetic rats
Keuper et al., Cell death & disease 2013 : The subsequent cleavage of PPAR? led to its inactivation and resulted in reduced expression of lipogenic genes, such as Glut-4 , FASN, and ACC