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E2F1 — NBN

Text-mined interactions from Literome

Frame et al., Oncogene 2006 : E2F1 induces MRN foci formation and a cell cycle checkpoint response in human fibroblasts ... Here, we show that E2F1 expression results in MRN foci formation, which is independent of the Nbs1 interacting region and the DNA binding domain of E2F1
Chen et al., Cell cycle (Georgetown, Tex.) 2011 : E2F1 deficiency results in defective NBS1 phosphorylation and foci formation in response to DSBs but does not affect NBS1 expression levels ... Moreover, an increased association between NBS1 and E2F1 is observed in response to DNA damage, suggesting that E2F1 may promote NBS1 foci formation through a direct or indirect interaction at sites of DNA breaks