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LATS1 — RASSF2
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Intact Interaction:
Complex of 16 proteins
(association, anti tag coimmunoprecipitation)
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IRef Intact Interaction:
Complex of 13 proteins
(association, anti tag coimmunoprecipitation)
-
IRef Intact Interaction:
Complex of 16 proteins
(association, anti tag coimmunoprecipitation)
-
IRef Intact Interaction:
Complex of 14 proteins
(association, anti tag coimmunoprecipitation)
Text-mined interactions from Literome
Matallanas et al., Mol Cell 2007
:
Subsequently,
RASSF1A activated
LATS1 phosphorylates and releases the transcriptional regulator YAP1, allowing YAP1 to translocate to the nucleus and associate with p73, resulting in transcription of the proapoptotic target gene puma
Hamilton et al., Curr Biol 2009
:
We show that, upon DNA damage,
RASSF1A is phosphorylated by ATM on Ser131 and is
involved in the activation of both MST2 and
LATS1 , leading to the stabilization of p73