◀ Back to IL6

CASP4 — IL6

Text-mined interactions from Literome

Hideshima et al., Oncogene 2001 (MAP Kinase Signaling System...) : We demonstrate that Dex induced apoptosis in MM.1S cells is mediated by downstream activation of caspase-9 , with resultant caspase-3 cleavage ; and conversely, that IL-6 triggers activation of PI3-K and its association with SHP2, inactivates caspase-9, and protects against Dex induced apoptosis
Ottonello et al., J Leukoc Biol 2002 (Granulomatous Disease, Chronic) : Accordingly, the spontaneous activity of caspase-3 was inhibited by GM-CSF, IL-6 , and IL-15
Böer et al., J Hepatol 2003 : By contrast IL-6 inhibited Fas induced increase in caspase-3 activity by 45 % and significantly reduced chromatin condensation
Guo et al., Blood 2003 : In the present study we confirm that Fas signaling induces both phenotypic and functional maturation of murine DCs, and we demonstrate that phenotypic maturation is associated with phosphorylation of extracellular signal regulated kinase ( ERK ) 1/2, activation of caspase-1 , and secretion of interleukin-beta ( IL-1beta )
Ma et al., Blood 2005 (Multiple Myeloma) : Baicalein inhibited the phosphorylation of IkB-alpha, which was followed by decreased expression of the IL-6 and XIAP genes and activation of caspase-9 and caspase-3
Wang et al., Ann Thorac Surg 2005 (Reperfusion Injury) : Myocardial tissue was then assessed for products of p38 MAPK activation, expression of tumor necrosis factor, interleukin-1beta and interleukin-6, and activation of caspase-1, caspase-3 and caspase-11 ... Myocardial tissue was then assessed for products of p38 MAPK activation, expression of tumor necrosis factor, interleukin-1beta and interleukin-6 , and activation of caspase-1, caspase-3 and caspase-11
Ueno et al., J Biol Chem 2006 (Carcinoma, Renal Cell...) : Consistent with these data, NEU3 markedly inhibited staurosporine induced caspase-3 activity and enhanced IL-6 dependent inhibition , which was abolished by LY294002, a PI3K inhibitor
Gustavsson et al., Retina 2008 (Diabetes Mellitus, Experimental...) : Ischemia induced increased expressions of TNF-alpha ( P < or= 0.012 ), IL-1beta ( P < or= 0.017 ), ICAM-1 ( P < or= 0.025 ), and IL-6 ( P = 0.012 ), and diabetes induced increased expression of caspase-1 ( P < or= 0.046 ), VCAM-1 ( P < or= 0.027 ), ICAM-1 ( P < or= 0.016 ), IL-1beta ( P = 0.016 ), and IL-6 ( P = 0.041 )
Boivin et al., Eur J Clin Invest 2010 (Kidney Failure, Chronic...) : Muscle atrophy in ESRD may be due to IL-6 induced activation of caspase-3 resulting in apoptosis as well as muscle proteolysis during HD
Shushanov et al., Bull Exp Biol Med 2010 : Insulin-like growth factor-1 and insulin inhibit caspase-3/7 activation initiated by interleukin-1ß in the rat eye retinal neurons
Kim et al., J Ethnopharmacol 2011 (Anaphylaxis...) : Additionally, IHT inhibited the production of interleukin (IL)-6 , IL-8, and TNF-a, as well as the activation of nuclear factor-?B and caspase-1 in PMACI stimulated HMC-1
Kannaiyan et al., Br J Pharmacol 2011 (Multiple Myeloma) : Celastrol also inhibited both the constitutive and IL6 induced activation of STAT3, which induced apoptosis as indicated by an increase in the accumulation of cells in the sub-G1 phase, an increase in the expression of pro-apoptotic proteins and activation of caspase-3
Tamai et al., J Dent Res 2012 (Chronic Periodontitis) : In addition, a caspase-8 inhibitor inhibited IL-6 production by amphotericin B and lipid A
Liao et al., Inflamm Res 2013 : Lipopolysaccharide/adenosine triphosphate mediated signal transduction in the regulation of NLRP3 protein expression and caspase-1 mediated interleukin-1ß secretion