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AKT2 — HSPD1
Text-mined interactions from Literome
Lai et al., Am J Physiol Endocrinol Metab 2007
(Diabetes Mellitus, Experimental) :
In the mitochondria depleted cells, overexpression of
HSP60 with adenoviral vector increased the abundance of IGF-I receptor, enhanced IGF-I activated receptor phosphorylation, and
augmented IGF-I activation of
Akt and ERK
Wang et al., Bone 2011
(Osteoporosis) :
HSP60 gene transfer
activated ERK and
Akt and reduced Bax and cytochrome c release, as well as caspase-3 cleavage, which attenuated the inhibitory effects of glucocorticoid treatment on osteoblast survival