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CD38 — PIK3CA

Text-mined interactions from Literome

Lewandowski et al., Br J Haematol 2002 (Cell Transformation, Neoplastic) : Interestingly, PI3-K activity was also necessary for CD38 expression on normal marrow CD34+ cells and for the ATRA induced upregulation of CD157, a CD38 related antigen ... In conclusion, PI3-K activity plays an essential role in the regulation of CD38 expression on human haematopoietic cells, and might constitute an interesting therapeutic target in haematological disorders involving CD38 overexpression
Jude et al., Am J Respir Cell Mol Biol 2012 (Asthma) : In HASM cells, regulation of CD38 expression occurs by specific class I PI3K isoforms, independent of NF-?B or AP-1 activation, and PI3K signaling may not be involved in the differential elevation of CD38 in asthmatic HASM cells