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AKT3 — RASA1
Text-mined interactions from Literome
Yue et al., J Biol Chem 2004
:
Overexpression of
RasGAP or a mutant lacking the GTPase activating domain ( nGAP )
enhanced phosphorylation and activity of
Akt , which was dependent on the upstream integrin linked kinase ... To determine the
role of
RasGAP in receptor mediated activation of
Akt , we used short hairpin RNA interference to knock out endogenous RasGAP expression
Chavez et al., J Biol Chem 2008
:
These results indicate that endogenous Tbc1d1 does not participate in insulin regulated GLUT4 translocation in adipocytes and suggest that the
GAP activity of Tbc1d1 is not
suppressed by
Akt phosphorylation
Bouzakri et al., Diabetes 2008
(Diabetes Mellitus, Type 2) :
Rab
GTPase activating protein AS160 is a major downstream
effector of protein kinase
B/Akt signaling in pancreatic beta-cells