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CD79A — MCL1

Text-mined interactions from Literome

Aichberger et al., Blood 2005 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive) : BCR/ABL dependent expression of MCL-1 in Ba/F3 cells was counteracted by the mitogen activated protein-kinase/extracellular signal regulated kinase ( MEK ) inhibitor, PD98059, but not by the phosphoinositide 3-kinase inhibitor, LY294002
Kohl et al., Leukemia 2007 (Acute Disease...) : In contrast to AML cell lines, BCR-ABL transformed human cells showed resistance to ABT-737, which might be due to the induction of MCL1 by BCR-ABL
Li et al., Oncogene 2007 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive) : Our data indicated that BCR/ABL induces SPK1 expression and increases its cellular activity, leading to upregulation of Mcl-1 in CML cells
Gobessi et al., Leukemia 2009 (Leukemia, Lymphocytic, Chronic, B-Cell) : In addition, R406 prevented the increase in leukemic cell viability induced by sustained BCR engagement and inhibited BCR induced Akt activation and Mcl-1 upregulation