Gene interactions and pathways from curated databases and text-mining

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DPYSL2 — MAP2K6

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: DPYSL2 → MAP2K6 (increases, DPYSL2 Activity)
    Evidence: to characterize changes in levels of proteins in MKK6 transgenic mouse hearts, focusing on proteins in mitochondria, which play key roles in mediating I/R injury in the heart. Of the 386 mitochondrial proteins identified, the levels of 58 were decreased, while only 2 were increased in the MKK6 transgenic mouse hearts